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The anti-inflammatory effect of choline was confirmed ex vivo, where endotoxin-activated human whole blood and macrophages exposed to supraphysiological choline concentrations (between 150 mM) exhibited reduced TNF- production (250)

(PubMed) Ebadi M, Montano-Loza AJ

However, there are very few reports in the literature on the protection provided by the application of l-carnitine to reduce the damage to the male reproductive system in the plateau environment [12]

Smoking is associated with free radical production resulting in high levels of DNA damage in human sperm and can affect the integrity of sperm DNA, which might result in increased incidences of childhood cancer in the offspring