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Konopleva M, Tabe Y, Zeng Z, Andreeff M

2026;4:1010132 DOI: Received: July 20, 2025 Accepted: March 18, 2026 Published: April 13, 2026 Academic Editor: Amnart Poapolathep, Kasetsart University, Thailand The article belongs to the special issue Neuroprotective Potential of Natural Products from Foods Aim: This study evaluated the comparative effects of commonly consumed artificial and natural sweeteners on cognitive function, neurotransmitter-related enzyme activities, and oxidative stress status in the brains of Wistar rats to elucidate their potential neurotoxic or neuroprotective properties under sub-chronic dietary exposure

Pathway enrichment analyses of the upregulated genes against MSigDB Hallmark 2020 database were performed via Enrichr

After being transported outside the cells, GSH is degraded by eukaryotic membrane-bound GGT which removes the -glutamyl moiety 28
