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showed that TMAO production was dependent on the gut microbiota and that mice treated with antibiotics failed to provide the required gut microbiota for TMAO production ( ApoE / mice without changing circulating cholesterol levels (75)

A decrease in Lactobacillus species was recorded in the L-carnitine and Mildronate groups, indicative of intestinal dysbiosis and a negative consequence of L-carnitine administration

Miller RA, Harrison DE, Astle CM, Fernandez E, Flurkey K, Han M, Javors MA, Li X, Nadon NL, Nelson JF, Pletcher S, Salmon AB, Sharp ZD, Van Roekel S, Winkleman L, Strong R

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