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Insufficient intake The most common cause of vitamin B12 deficiency is insufficient intake (absorption), which can be caused by the following: excessive bacterial growth in the small intestine impaired absorption (malabsorption) due to coeliac disease [1] or a disease of the pancreas inflammatory diseases of the small intestine (vitamin B12 is absorbed in the small intestine) surgery on the gastrointestinal tract

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Instead, its activity is believed to be mediated via adipocyte-specific signaling cascades, which gives the fragment a uniquely narrow pharmacological footprint for a peptide of its molecular size and makes it attractive to investigators who want clean lipolytic readouts

Hydroxocobalamin (a.k.a