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4.5 Metabolic dysregulation 4.5.1 Insulin signaling pathways in obesity and metabolic disease Metabolic tissues develop lipid intermediates alongside altered adipokine expression profiles and compromised mitochondrial function, progressively attenuating insulin responsiveness (158)

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[2] Cell Line:MCF-7 human breast cancer cell Concentration:10 -5 M, 10 -4 M, 10 -3 M Incubation Time:6 d Result:Did not stimulate MCF-7 cell proliferation at any tested concentration

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