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This increased nitrosative and oxidative stress results in activation of poly(ADP-ribose) polymerase-1 (PARP-1) to prevent DNA damage [366]
Preoperative severe vitamin D deficiency is a significant independent risk factor for poorer functional outcome and quality of life 6 months after surgery for fragility hip fractures
Another FDA-approved weight loss medication, a combination of phentermine and topiramate, used in conjunction with lifestyle modification in a late-stage trial, produced significant two-year sustained weight loss in overweight and obese volunteers
FIERCE Pharma (2020)
