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Histidine and arginine are associated with inflammation and oxidative stress in obese women

Heme oxygenase-1 induction by NRF2 requires inactivation of the transcriptional repressor BACH1

The authors thank Figdraw for image drawing and AJE for language check
Notably, the ligand for IGF1R, insulinlike growth factor 2 (IGF2), increases BACH1 expression via the IGF1RERK1/2ETS1 pathways, creating a feedback mechanism that exacerbates HCC progression and metastasis
