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doi: 10.1038/cmi.2010.1

Histone methylation: a dynamic mark in health, disease and inheritance

Several causative factors, including ammonia, inflammation, neuroinflammation, and oxidative stress, contribute to its pathogenesis, ultimately leading to abnormalities in neurotransmission and altered neuronal integrity
To assist in the non-invasive evaluation of liver fibrosis and guide treatment strategies, clinical scoring systems like FIB-4, along with transient elastography, have been developed to facilitate risk stratification (Figure 2) [2]