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Dietary supplements present a documented risk for anti-doping violations because they remain outside WADA regulations and are frequently contaminated
Association of vitamin B12 deficiency in people with type 2 diabetes on metformin and diabetic peripheral neuropathy Nature article: Shows prolonged metformin use correlates with lower B12 and more severe diabetic neuropathy
doi: 10.1002/j.1552-4604.1997.tb04342.x

Since the extent of spine remodeling correlates with success of learning, this suggests a crucial role of synaptic structural plasticity in memory formation
